Harnessing cutting-edge array-based DNA synthesis

28 Jul 2025
Cameron Smith-Craig
Cameron Smith-Craig
Pharma and Applied Sciences Editor

The capability to synthesize nucleic acids in the laboratory has revolutionized life sciences, fueling the rapid growth of synthetic biology. As the range of synthetic biology applications continues to expand, so too does the demand for increasingly complex, highly precise, and longer oligonucleotide libraries.

Explore this eBook to uncover the latest DNA synthesis platforms that offer customizable complexity to assemble oligonucleotide libraries for your workflows, and read of real-world applications that have harnessed this technology and overcome common hurdles in the design and assembly of oligonucleotide libraries.

Download for free to explore:

  • Complex protein modelling that supports design for better diagnostics, therapeutics, and other protein-based applications
  • Genetic mutations and their influence in cancer progression
  • Innovations in protein engineering for the development of next-generation therapeutics
  • COVID-19 studies to advance understanding and therapeutic targeting

SurePrint oligonucleotide libraries

Agilent Technologies

The Agilent SurePrint platform delivers high-quality oligo pools perfectly suited for applications in protein engineering, gene assembly, pooled CRISPR screening, and more. Agilent oligo pools offer custom, high resolution, massively parallel DNA synthesis available in standard or HiFi options in a broad range of sizes.

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DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.DNA SynthesisCovid-19COVID-19, caused by the SARS-CoV-2 virus, has led to a global health crisis with profound impacts on societies and economies. Research into diagnostics, vaccines, treatments, and understanding viral mechanisms continues to evolve. The pandemic has accelerated innovations in healthcare and biopharmaceuticals, including novel vaccine platforms and rapid testing technologies. Browse our peer-reviewed product directory to find top COVID-19 testing kits, research tools, vaccines, and treatments, compare products, read reviews, and receive direct pricing from manufacturers.Cancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.