Gravimetric calibration and testing of piston-operated volumetric apparatus

Reliable and reproducible liquid handling results depend on the regular testing and calibration of instruments. Globally, the most accepted International Standardization Organization (ISO) standard that details requirements for producing and in-use control of piston-operated volumetric apparatus (POVA) is the ISO 8655. In this white paper, Sartorius presents the requirements for gravimetric calibration and testing of POVA according to part 6 and part 7 of the ISO 8655, revised in 2022. Furthermore, the differences between calibration and testing according to chapters 6 and 7, which describe the testing method, testing environment, testing equipment, and reporting requirements, will be explored.