ResourceLife Sciences
Gene Expression Analysis: A Review
19 Nov 2012This whitepaper from Plexpress provides a comprehensive review of the major methods available for gene expression analysis including microarrays, RNA sequencing, qPCR and transcript analysis and affinity capture (TRAC). The technical, time and cost implications of each method are compared. The applications of the TRAC platform in ADME-Tox, yeast culture optimization and cancer, metabolic diseases and biomarker research are described. Choice of gene expression analysis technologies are dependent on specific study needs and, with the many genome-wide and targeted options available, deciding on the best approach can be challenging. The whitepaper aims to simplify the reader’s choice of gene expression analysis by providing detailed information on each method’s applications, strengths and weaknesses.
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PlexpressOneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling for genome-wide and focused-gene analyses
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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. 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Explore RT-qPCR systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cytochrome P450 Assays