SelectScience
Join Free
Accelerating Science
ResourceSeparations

GC-TOFMS Study on Common Drugs of Abuse: Diphenylhydramine, Orphenadrine, Propoxyphene, Amitryptyline and Dothiepin

LECO Corp.
21 May 2012

This note describes the analysis of some common drugs of abuse by Gas Chromatography—Time-of-Flight Mass Spectrometry (GC-TOFMS). In addition to using standards, two real-life samples of blood and urine extracts were analyzed to demonstrate the power of the technique in handling samples containing small amounts of drugs in demanding matrices.

Related products

Request Quote for All Products

Pegasus® GC-HRT

LECO Corp.

While some systems on the market offer users a choice between acquisition speed or resolution, the Pegasus GC-HRT provides scientists with an unprecedented combination of speed, resolution, mass accuracy, isotopic abundance, and dynamic range. This instrumentation utilizes LECO's own Folded Flight Path™ (FFP™) technology to allow users to achieve resolutions of up to 50,000. LECO's exclusive ChromaTOF-HRT™ software with Automated Peak Find and True Signal Deconvolution® provides seamless data handling and compatibility with the NIST Library.

(3)

Links

LECO Corp.Company website

Tags

Toxicology / Drugs of Abuse TestingToxicology and Drugs of Abuse Testing is the investigation into toxic and illegal substances found at the scene of a crime or from a suspect and / or victim associated with a scene of a crime. Analyzers, immunoassays and drugs of abuse test kits and presumptive test kits are an essential aspect of toxicology investigation.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DiphenylhydramineOrphenadrinePropoxypheneAmitryptylineDothiepinAnti-Doping ScienceAnti-doping science involves the detection of performance-enhancing drugs (PEDs) and banned substances in athletes. This field helps ensure fair competition and athlete safety. Explore anti-doping science tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

Related resources

GC-TOFMS Study on Common Drugs of Abuse: Diphenylhydramine, Orphenadrine, Propoxyphene, Amitryptyline and Dothiepin