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Fully Automated GC/MS Determination of Amino Acids

Gerstel GmbH & Co. KG
10 Oct 2016

Some metabolic disorders can be diagnosed by determining amino acid concentration levels. The ideal tool for the determination of amino acids in biological matrices is gas chromatography combined with mass spectrometry (GC/MS), but in order to meet the efficiency requirements of modern diagnostic laboratories, the analytical procedure needs to
be highly automated.

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MultiPurpose Sampler (MPS)

Gerstel GmbH & Co. KG

The MultiPurpose Sampler MPS is a multifunctional autosampler and sample preparation robot for GC (GC/MS), LC (LC/MS) and standalone operation. Sample preparation steps are performed during the analysis of the preceding sample for best system utilization and highest sample throughput. Sample preparation steps are performed in a controlled and highly accurate and reproducible manner for best possible results. Every step is selected by mouse-click form a pull-down menu in the GERSTEL MAESTRO software and added to the overall GC/MS or LC/MS method. Available sample preparation steps are: Derivatization and Standard addition Dilution and extraction Cooled or heated conditioning and mixing Sonication and Centrifugation Automated weighing of liquid samples and standards Solid Phase Extraction SPE Disposable Pipette Extraction DPX Automated Twister desorption and analysis Twister Back Extraction TBE Automated GC inlet Liner EXchange ALEX Dynamic Headspace DHS Thermal Desorption and Thermal Extraction

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GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Amino AcidsMetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.GC-MSGas Chromatography-Mass Spectrometry (GC-MS) combines the separation power of gas chromatography with the detection capabilities of mass spectrometry, allowing for the analysis of complex mixtures. It is widely used in environmental, forensic, and pharmaceutical analysis. Explore GC-MS systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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