Fully automated cell culture passaging and expansion using decision making-based image analysis

19 Aug 2025

In this application note, we demonstrate how the CellXpress.ai Automated Cell Culture System uses AI-driven image analysis to enable fully automated passaging, media exchange, and expansion of HCT116 and CHO cells, improving reproducibility, efficiency, and walk-away cell maintenance for drug discovery and research.

CellXpress.ai Automated Cell Culture System

Molecular Devices®

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Fully automated cell culture passaging and expansion using decision making-based image analysis