ResourceLife Sciences
From QC to quantitation: Utility of QReSS metabolites in FBS measurements
24 Nov 2025Metabolomics is a rapidly growing field of research that has unique and proven advantages in systems biology and biomarker discovery. Great advances have been made over the past decade on the feasibility of mass spectrometry (MS)-based metabolomics. Despite the advancements, there remains a pervasive need for quality control (QC) as metabolomic experiments can experience unwanted variations that threaten the quality of the acquired data. The use of reliable QC measures is therefore critical to assess and prevent unwanted preanalytical and instrumental variation.
In this application note, the QReSS™ standard mixes (CIL cat no. MSK-QReSS1 and MSK-QReSS2) were used in the QC of metabolites from variably sourced FBS samples.
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.