FFPE RNA quality assessment with the Agilent Bioanalyzer and TapeStation Systems

16 Jun 2025

In this application note, Agilent Technologies highlights the capabilities of both the Agilent Bioanalyzer and TapeStation systems in analyzing FFPE RNA samples using the DV200 score. The results provide a comparison between the DV200 scores from each system.

4200 TapeStation Instrument

Agilent Technologies

The Agilent 4200 TapeStation system is an established automated electrophoresis tool for DNA and RNA sample quality control. Fully automated sample processing enables the unattended analysis of size, concentration and integrity. Choose any sample number between 1 and 96 and analyze at constant cost per sample.

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2100 Bioanalyzer

Agilent Technologies

The Agilent 2100 Bioanalyzer is a microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells on a single platform. Results are delivered within 30-40 minutes in automated, high quality digital data. The Agilent 2100 Bioanalyzer system provides sizing, quantitation and quality control of DNA, RNA, proteins and cells on a single platform, providing high quality digital data.A unique feature of the Agilent 2100 bioanalyzer is that it can be used for both electrophoretic separation and flow cytometric analysis of cell fluorescence parameters. This versatility makes the Agilent 2100 bioanalyzer an indispensable tool for the molecular biologist and biochemist.2100 Bioanalyzer Features: Ready-to-use assays and pre-packaged reagent kits Minimal sample consumption (1-4 µL) and results within 30 minutes Replaceable electrode cartridge for contamination-free switch of methods Improved assay accuracy and precision Comparable results from lab to lab Digital data for convenient analysis, archiving and storage Various data-display options as gel view, electropherograms and tables Easy to use with simplified sample comparison Minimum exposure to hazardous materials Supports compliance with 21 CFR Part 11

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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FFPE tissueRNARNA is a nucleic acid that plays a key role in gene expression and protein synthesis. It serves as a messenger between DNA and ribosomes, carrying genetic instructions to produce proteins. Advances in RNA-based therapies, such as mRNA vaccines and gene editing, have revolutionized treatment strategies for genetic disorders and infectious diseases. Explore RNA research tools and therapies in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.
FFPE RNA quality assessment with the Agilent Bioanalyzer and TapeStation Systems