ResourceSpectroscopy
Fast Track Mass Spec Sample Prep
20 Sept 2018Mass spectroscopy (MS) is a ubiquitous characterization tool that is vital to biologics development. Unfortunately many MS experiments require a compatible sample solution that differs from the supplied formulation to acquire high quality mass spectra. For example, electrospray ionization (ESI) experiments require a solution of water, organic solvent and organic acid as well as the removal of salts, detergents and buffering molecules. To remove these unwanted buffer components and to hit the right solution conditions, buffer exchange and/or dilution are commonly used.
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.BiologicsBiologics are medical products derived from living organisms, including vaccines, gene therapies, and monoclonal antibodies. These treatments are key to modern healthcare, especially in oncology and autoimmune diseases. Explore biologics research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.