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Enrichment of low abundance, low molecular weight proteins from human plasma samples

Enrichment of low abundance, low molecular weight proteins from human plasma samples

23 Dec 2019

In this application note, Ceres Nanosciences provides a brief description of the Nanotrap® particle technology platform and presents the results of an experimental protocol for enrichment of low-abundance proteins prior to proteolytic digestion, fractionation by liquid chromatography, and analysis by mass spectrometry.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. NanoparticlesNanoparticles are between 1-100nm in size. Nanoparticles can be used for a wide variety of applications including biomedical, catalysis and electronics.
Enrichment of low abundance, low molecular weight proteins from human plasma samples