ResourceLife Sciences
Enhanced epigenetic profiling using target enrichment of single cell methylation libraries
4 Feb 2025DNA methylation patterns are critical disease markers in acute myeloid leukemia (AML) implicated in tumorigenesis, progression, and therapeutic responses. Explore the compatibility between Scale Bio Single Cell Methylation libraries and the Twist Biosciences Human Methylome Panel on peripheral blood mononuclear cells (PBMCs) derived from an acute myeloid leukemia patient.
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Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Acute Myeloid LeukemiaDNA MethylationEpigeneticsEpigenetics refers to heritable changes in gene expression. These changes are not caused by alterations to the DNA sequence. Three of the main systems responsible for the initiation of epigenetic change are DNA methylation, histone modification and non-coding RNA-associated gene silencing.Target-Enrichment