ResourceLife Sciences
Endothelial cell transmigration and invasion assay
12 Oct 2020Angiogenesis is the physiological development of new blood vessels from existing ones, a process that is essential for embryonic and fetal development and organ growth, supports the healing of wounds and skeletal growth, and is also an integral part of pregnancy and the female reproductive cycle. The key challenge in angiogenesis research is still selecting the right combination of in vitro and in vivo assays from the wide available range for obtaining meaningful and translatable results. In this application note, PromoCell provides a robust, rapid and reproducible assay with a reliable readout, in order to study angiogenesis in all its variety.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.AngiogenesisCell InvasionAssay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.