Endonuclease treatment in downstream processing of virus-like particles
29 Oct 2024In a head-to-head comparison with Benzonase, M-SAN HQ delivers superior results in Lentiviral vector purification — boosting both yield and purity while effectively degrading chromatin contaminants. This advanced nuclease operates seamlessly at physiological salt levels, minimizing aggregation risks and streamlining downstream processing.
Explore the data from acib (Austrian Centre for Industrial Biotechnology), a non-profit internationally recognized research center, and understand why M-SAN HQ is becoming the preferred choice in viral purification. Discover how integrating M-SAN HQ can enhance viral vector production, ensuring high-purity outputs critical for meeting regulatory standards.
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Endonucleases DNA-specific
ArcticZymesDouble-Strand Specific dsDNase from ArcticZymes is ideal for removing contaminating DNA from PCR master mixes, preventing false positives in bacterial typing. Recombinantly produced in Pichia pastoris, it cleaves dsDNA with 5000-fold higher specificity than ssDNA. Easily inactivated by moderate heat (65°C), it allows for direct addition of DNA templates post-cleanup, ensuring accurate PCR results.