ResourceLife Sciences
Early detection of aggregation in formulations: FlowCam Nano for submicron particle characterization in biotherapeutics
17 Mar 2022In this white paper, Yokogawa Fluid Imaging Technologies demonstrates the utility of FlowCam Nano in biotherapeutic development by analyzing solutions containing protein aggregates, sucrose aggregates, and E. coli cells using traditional subvisible and submicron FIM.
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FlowCam Nano
Yokogawa Fluid Imaging Technologies, IncFlowCam® Nano provides dynamic image analysis of submicron particles from 300 nm to 2 µm, bridging the gap between traditional flow imaging microscopy and other particle analysis techniques. Use FlowCam Nano for early detection of aggregates and contaminant monitoring for protein formulations, nano-drug delivery systems, characterization of bacteria, bioprocess monitoring, and materials characterization.
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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AggregationBiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.