dTAG protein degradation assay for the targeted degradation of proteins of interest

23 Oct 2024

Targeted protein degradation is a novel strategy with the aim to selectively eliminate specific proteins from cells for therapeutic reasons. Degradation TAG (dTAG) technology is an innovative approach to target validation. Explore how using the dTAG protein degradation assay, tested dTAG molecules were successfully employed to induce the targeted degradation of the HiBiT-fusion protein complex.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.
dTAG protein degradation assay for the targeted degradation of proteins of interest