ResourceLife Sciences
Discover the Selvita cell painting service
10 Oct 2023Cell Painting is a highly multiplexed image-based assay used for cytological profiling. The captured information can be translated via automated image analysis into thousands of numerical features that are used to generate morphological profiles reflecting the biological state of the cells. In this application note from Selvita, explore how the comparison of morphological profiles serves multiple purposes. It can identify the phenotypic impact of chemical or genetic perturbations, elucidate the mode of action, and reveal off-target effects of potential drugs. Therefore, the cell painting methodology can be employed in both preclinical and early discovery programs, providing novel mechanistic insights.
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In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.