Direct protein quantitation using the SpectraDrop Micro-Volume Microplate

11 Mar 2025

This application note highlights the use of the SpectraDrop Micro-Volume Microplate for rapid, low-volume protein quantitation via UV absorbance. The plate’s innovative design, featuring a Teflon-coated slide and adjustable path lengths, enables accurate measurement of BSA concentrations ranging from 0.012 mg/mL to 100 mg/mL — eliminating the need for sample dilution. Ideal for high-throughput workflows, the SpectraDrop plate streamlines protein analysis with sample volumes as low as 2 µL.

SpectraDrop Micro-Volume Microplate

Molecular Devices®

Formerly known as MicroMax, Molecular Devices’ unique SpectraDrop™ Micro-Volume Microplate, offers the highest throughput solution for low volume measurement available onthe market today. Innovative and flexible design features enable accelerated sample preparation time and increased laboratory productivity of DNA, RNA, and protein samples as low as 2 µL. The SpectraDrop™ Micro-Volume Microplate assures uniform and reproducible analysis and integrates seamlessly with the StakMax® Microplate Handling System for greater research capacity.

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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein Quantitation
Direct protein quantitation using the SpectraDrop Micro-Volume Microplate