Development of Simple, Robust and Highly Sensitive Cell-Based Assays for the Valiscreen™ TRPC3 and TRPC6 Cell Lines

16 Aug 2012

Read this poster to learn about how ValiScreen™ human TRPC3 and TRPC6 recombinant HEK-293 cell lines (PerkinElmer), were developed and characterized in cell-based assays using Membrane Potential fluorescent dyes on a FLIPRTETRA® system (Molecular Devices), and manual patch-clamp.

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ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.Patch ClampReceptorsIon Channel
Development of Simple, Robust and Highly Sensitive Cell-Based Assays for the Valiscreen™ TRPC3 and TRPC6 Cell Lines