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Developing New Methods for Pesticides in Dietary Supplements

Restek Corp.
1 Apr 2011

In this application note a procedure is demonstrated that incorporates a QuEChERS extraction, cSPE cleanup and GCTOFMS, resulting in good recoveries for a wide range of pesticide chemistries in dandelion root powder. This approach saves time and can reduce analyst variation by minimizing manual preparation with prepackaged extraction salts and snap-and-shoot standards. Analytical benefits include reduced interferences and good recoveries, even of polar compounds.

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Q-sep™ QuEChERS Tubes

Restek Corp.

Q-sep™ QuEChERS Tubes for Pesticide Residue Analysis • Fast, simple sample extraction and cleanup using dSPE. • Fourfold increases in sample throughput. • Fourfold decreases in material cost. • Convenient, ready to use centrifuge tubes with ultra pure, preweighed adsorbent mixes. Quick, Easy, Cheap, Effective, Rugged, and Safe, the QuEChERS ("catchers") method, developed by the USDA Eastern Regional Research Center, has become very popular for extraction and clean-up of pesticide residue samples. Our products are available in three centrifuge tube sizes to meet the needs of both extraction and cleanup of a wide variety of sample matrices following various methods. The researchers developed a simple two-step procedure. First, the homogenized samples are extracted and partitioned, using an organic solvent and salt solution. Then, the supernatant is further extracted and cleaned, using a dispersive SPE technique. Multiple adsorbents are placed in a centrifuge tube, along with the 1mL of organic solvent and the extracted residues partitioned from step 1. The contents are thoroughly mixed, then centrifuged, producing a clean extract ready for a variety of GC or HPLC analytical techniques. Validation and proficiency data for the QuEChERS method are available for a wide variety of pesticides in several common food matrices on their website.

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Rxi®-5Sil MS (Fused Silica) Columns

Restek Corp.

Rxi® fused silica capillary GC columns were designed specifically to be the best columns available, for exceptional inertness, ultra-low bleed, and reproducible retention and selectivity.

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Developing New Methods for Pesticides in Dietary Supplements