Determining Detection Limits of Infinite® Multimode Readers Using the Glowell™ GLO-466 Standard

20 Mar 2015

Gaseous luminescence standards – such as Glowell standards – are certified calibration reference materials offering a stable, pre-measured light output generated by a chemical light source. This application note determines the luminescence detection limits of Infinite series multimode readers using a gaseous standard measured in a black microplate. Determining the detection limit in this way provides an artificial measure of instrument performance, as the signal-to-noise is limited to almost zero.

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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.
Determining Detection Limits of Infinite® Multimode Readers Using the Glowell™ GLO-466 Standard