ResourceSeparations

Determination of Ethyl Sulfate Impurity in Indinavir Sulfate Drug using Ion Chromatography

29 Nov 2011

This work shows IC separation of ethyl sulfate in an indinavir sulfate drug sample. The method only requires the addition of DI water to the IC system to deliver reproducible chromatography while avoiding the time, labor, and potential error of manual eluent preparation. It uses an electrolytic suppressor in recycle mode, and therefore does not require the analyst to prepare sulfuric acid solutions for eluent suppression prior to conductivity detection.

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Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Indinavir SulfateEthyl SulfateElectrolytic Suppressor
Determination of Ethyl Sulfate Impurity in Indinavir Sulfate Drug using Ion Chromatography