ResourceLife Sciences
Designing label-free biosensor assays for Fc receptor binding analysis
17 Mar 2025Understanding Fc gamma receptor (FcγR) binding kinetics is critical for biotherapeutic development. This application note explores label-free biosensor assays using Alto™ Digital SPR™, highlighting best practices for assay optimization, immobilization strategies, and data analysis to enhance antibody characterization.
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Alto™ Digital SPR™
NicoyaTransform biomolecular interaction analysis with Alto™, the world’s first Digital SPR™ system, featuring zero maintenance and cartridge-based characterization from ultra-low sample volumes.
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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiosensorsSurface Plasmon ResonanceMonoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.KineticsBiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.Label-Free Analysis