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Cubis II loss on drying: Determining dry weight of tablets, capsules or bulky materials

16 Feb 2021

In this application note, Sartorius explains how loss on drying is a back-weighing application to determine the amount of volatile matter in tablets, capsules, or bulky material, where samples are weighed before and after treatment, and the weight difference is measured.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Balances and Moisture AnalyzersBalances & Moisture Analyzers / weighing scales measure static or dynamic loads. Features to consider when choosing an analytical balance include accuracy, capacity and resolution. Additional features and specialized balances include enclosures for weighing powder, microbalances for measuring small quantities, portable balances, moisture analyzers, top loading balances and internal calibration for measurements over time or with varied temperature.Drug TestingIt is essential to test the efficacy and toxicity of drugs at every stage of their development to ensure that a pharmaceutical product is fit for purpose and safe for use before reaching the stage of mass production and distribution.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.
Cubis II loss on drying: Determining dry weight of tablets, capsules or bulky materials