ResourceLife Sciences
CRISPR-mediated transcriptional repression poster
17 Nov 2021First-generation CRISPRi systems utilize the Krüppel associated box (KRAB) domain from zinc finger protein 10 (KOX1) fused to dCas9 (dCas9- KRAB) as a transcriptional repressor, an approach shown to be more target-specific than other existing technologies for gene repression. Given that this CRISPR-based approach can also result in less robust repression of the target gene(s), there is a need for identifying ways to improve its efficiency. Download this poster by Horizon Discovery to find out the results of its study on CRISPR-mediated transcriptional repression.
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Protein ExpressionProtein expression is the utilization of cell machinery for the synthesis of proteins and has become a critical tool in biotherapeutic, genomic, and proteomic research. Produce recombinant proteins with expression vectors in combination with a host cell suitable for high-level protein expression. For production of toxic proteins, consider cell-free expression vectors. Create and monitor post-translational modifications with protein modification kits. Find the best protein expression products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RNARNA is a nucleic acid that plays a key role in gene expression and protein synthesis. It serves as a messenger between DNA and ribosomes, carrying genetic instructions to produce proteins. Advances in RNA-based therapies, such as mRNA vaccines and gene editing, have revolutionized treatment strategies for genetic disorders and infectious diseases. Explore RNA research tools and therapies in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Synthetic BiologyCRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.