ResourceLife Sciences
Covaris: streamlining protein digestion from mammalian cells
29 Oct 2024Over the past 20 years, breakthroughs in analytical technologies like LC-MS have transformed proteomics from a purely research-focused area to a field with significant applications in clinical research and biopharma, directly benefiting patients. However, achieving high-quality proteomics data is not possible without a robust sample preparation protocol. Discover how Covaris developed a comprehensive workflow with Covaris truPREP® Protein Kit that ensures extraction, purification, and accelerated digestion for a wide range of mammalian cells.
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Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein CaptureTrypsin