Contrast in oligonucleotides

20 Jun 2025

In this product brochure, discover the differences between Sigma-Aldrich® oligonucleotides: Research-Use-Only (RUO) and current good manufacturing practice (cGMP, manufactured in accordance with US GMP 21 CFR 820).

Custom cGMP Oligos

Merck

If you commercialize Molecular Diagnostics (MDx), create Laboratory Developed Tests (LDTs), or conduct preclinical research, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards. In the case of oligonucleotide raw materials available with custom specifications, the only option you should consider is Custom cGMP Oligos.

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OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.Oligos
Contrast in oligonucleotides