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Comparison of the CETAC MVX‐7100 Micro‐Volume Workstation with an Established Laboratory Method for the Assessment of Lead, Mercury, and Arsenic in Human Whole Blood

Comparison of the CETAC MVX‐7100 Micro‐Volume Workstation with an Established Laboratory Method for the Assessment of Lead, Mercury, and Arsenic in Human Whole Blood

4 Dec 2015

Conventional autosamplers used in clinical ICP‐MS are largely based on the needs of non‐clinical environments. Their disadvantages are numerous and include high sample volume consumption, large dead volumes resulting in wasted sample, and the inability to integrate easily with high throughput formats such as 96 and 384 well plates. Further, use of a low‐volume autosampler allows for a reduction in reagents translating into an overall reduction in costs. This application note demonstrates a method for the analysis of lead, mercury and arsenic in human blood using the Agilent 7700x with a CETAC ASX‐510 HS autosampler.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Heavy MetalsClinical ChemistryClinical chemistry involves the analysis of bodily fluids, like blood and urine, to diagnose and monitor diseases. Tests in clinical chemistry provide critical information for patient care and treatment decisions. Explore clinical chemistry tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.LeadBlood AnalysisThe analysis of blood is vital for many areas of life sciences and forensic investigations. Blood samples can be tested for a number of different reasons such as diagnosis, glucose levels, cholesterol and drug testing.ArsenicArsenic is a toxic element that is used in the production of pesticides. Arsenic contamination of groundwater is a major issue for both drinking water and for uptake in foodstuffs such as rice.MercuryCalibration
Comparison of the CETAC MVX‐7100 Micro‐Volume Workstation with an Established Laboratory Method for the Assessment of Lead, Mercury, and Arsenic in Human Whole Blood