Compact Sequencing Technology for KRAS Companion Diagnostic Testing

17 Feb 2013

Certain KRAS gene mutations are often present in patients with colon, lung and pancreas cancer. Therapeutic antibodies Erbitux® and Vectibix® are only effective treatment options in patients without KRAS gene mutations. This poster describes how compact sequencing technology can be used as a fast and cost effective alternative to established PCR methods.

Hybcell - DNA or protein microarray

Anagnostics Bioanalysis

Anagnostics' hybcell is the world's first DNA or protein microarray based on the use of cylinders instead of slides. hybcell technology is... KINETIC - by means of consecutive scans, FAST - with help of rotational sample agitation, FLEXIBLE - due to fixed starting temperatures, flexible temperature profiles and computer-controlled buffer exchange and EFFICIENT - by automated processing and electronically documenting of up to 96 samples in a single run.

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Hyborg - cylindrical DNA and protein analysis

Anagnostics Bioanalysis

Hyborg is a fully automated device for processing and analysing hybcells (cylindrical DNA and protein microarrays). Hyborg integrates thermocycler, hybridisation station and scanner into a single device. All processing steps - from temperature profiles or exchange of liquids to multi-color scanning - are computer-controlled and documented. Hyborg's concept of totally integrated automation guarantees maximum reproducibility of assays. Autonomous processing of up to 96 hybcells reduces hands-on-time to a minimum and provides maximum ease of use.

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