Combination of Flow With 3D Cell Culture Improves Metabolic Competency in Multiple Cell Types

23 Sept 2012

Cell culture typically involves growing cells in 2D under static conditions. This is not always however sufficient to representative the in vivo environment and cells can exhibit different characteristics than they would in the host organism. The Quasi-Vivo culture system, from Kirkstall, has been developed to enable 3D cell culture under laminar flow. This scientific poster, presented at ELRIG Drug Discovery 2012, demonstrates the advantages of flow and 3D culture for various cell types. The Quasi-Vivo culture system enables cells to be subject to the same shear stress and pressure as they would be in vivo and allows cells to interact with one another, thus allowing cell signaling to be investigated.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.ELRIG
Combination of Flow With 3D Cell Culture Improves Metabolic Competency in Multiple Cell Types