ResourceSeparations
Class-Selective Enantiomeric Separation of β-Androgenic Receptors using CHIROBIOTIC™ T Stationary Phase
30 Apr 2012The inherent chirality of bio-organic molecules and its affect on biological activity creates a growing need for chiral separations. This application note demonstrates the chiral separation of β-androgenic receptors, a class of pharmaceutically active compounds using both UV and MS detection.
The CHIROBIOTIC T stationary phase was chosen for the study. CHIROBIOTIC T has unique selectivity for a number of classes of molecules including carboxylic acids, phenols, neutral aromatic analytes, and cyclic aromatic and aliphatic amines. Moreover, the CHIROBIOTIC T provides chiral separation using reversed-phase solvent mobile phases.
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