ResourceSeparations

Characterizing of the Natural Product Goldenseal Using CORTECS 2.7 µm Columns and ACQUITY QDa Detection

5 Jan 2015

In this application note, five different sources of Goldenseal, which span four different manufacturers, two different parts of the plant, and two different formulation matrices are analyzed. This variety of sources was tested to determine the differences between each sample and if there were any compounds common to all the tested sources. Each sample was analyzed using a CORTECS C18+, 2.7 µm, 3.0 x 50 mm Column on an Alliance HPLC System with both UV and an ACQUITY QDa Detector in order to get fast and reliable mass data for peaks present in the sample, providing additional and crucial information for the characterization of the natural products.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Natural Products
Characterizing of the Natural Product Goldenseal Using CORTECS 2.7 µm Columns and ACQUITY QDa Detection