Characterization of GPCR’s Signaling Signature Using the Novel Biosensor Platform, BioSens-All™

13 Feb 2015

A novel biosensor platform BioSens-All™, with over 25 biosensors, was implemented to elucidate the multiple signaling events associated with GPCR activation. The system enabled the classification of sets of compounds according to their functional selectivity, leading to identification of modulator validated pathways.

Tags

BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.gPCRSLASThe Society for Laboratory Automation and Screening (SLAS) is an organization focused on laboratory automation, high-throughput screening, and biotechnology innovation. SLAS promotes scientific advancements through conferences, publications, and industry collaborations.
Characterization of GPCR’s Signaling Signature Using the Novel Biosensor Platform, BioSens-All™