Cellular Analysis Using the Coulter Principle: Measurement with Great Accuracy and Speed

1 Apr 2015

Whether your cells are bacteria, animal cells or plankton, this white paper discusses how the Coulter Principle is one of the most universal and adaptable techniques for studying cell size or simply counting cells. It has been a stable and proven technology since it was developed in the late 1940’s. In this guide a number of methodologies utilizing the Coulter Principle are presented together with some typical examples.

Multisizer 3 Coulter Counter

Beckman Coulter Diagnostics

The Multisizer 3 is the next generation in particle sizing and counting.The most versatile particle sizing and counting analyser available today, the Multisizer 3 provides number, volume, mass, and surface area size distributions in one measurement, with an overall sizing range of 0.4 to 1200 microns.Whatever the industry – abrasives, pharmaceuticals, polymers or biological cell studies – you will get the ultra-high resolution, multiple channel analysis and accuracy you need. The response is unaffected by particle colour, shape,density, composition or refractive index.Equally at home in a quality control environment or Research and Development laboratory, the Multisizer 3 Coulter Counter provides the analyst with a system which is easy to use, yet so technologically advanced that it is able to solve most particle sizing or counting problems.

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Multisizer 4e Coulter Counter

Beckman Coulter Diagnostics

The Multisizer 4e, the latest COULTER COUNTER designed with the SMART and DPP technologies, offers highly accurate and reliable particle counting and sizing. Discover the most versatile and accurate particle sizing and counting analyzer on the market.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.
Cellular Analysis Using the Coulter Principle: Measurement with Great Accuracy and Speed