Cell Viability Assays with Mithras LB 940

24 Jun 2013

Actinomycin D is used as an anti-mitotic and an intercalating agent of DNA. It inhibits the synthesis of mRNA by intercalation into the DNA strand and thereby preventing the polymerase activity. In this application note read how the effects of two concentrations of Actinomycin D were tested on CHO cells. The cellular viability of those cells was assessed by different cell viability agents/assay kits like Alamar Blue (Invitrogen), UptiBlue (Interchim) and Resazurin (Interchim).

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell ViabilityCell viability assays assess the health of cells and their ability to proliferate. These tests are crucial in drug development, toxicity testing, and cell-based research. Common methods for assessing viability include MTT, live/dead assays, and flow cytometry. Browse our peer-reviewed product directory to find the best tools for cell viability assays, compare products, check reviews, and get pricing directly from manufacturers.
Cell Viability Assays with Mithras LB 940