Calibration of NAB-Sure Neutralizing Antibody Titer using WHO International Standard

28 Oct 2024

NAB-Sure™ is a cell-free neutralizing antibody assay that offers sensitivity and precision when measuring anti-SARS-CoV-2 neutralizing antibodies. Explore how Spear Bio calibrated NAB-Sure neutralizing antibody titers to the international units using the second WHO international standard. This calibration enables a direct comparison of NAB-Sure’s neutralizing antibody measurements with other IU-calibrated assays, enabling broader and more accurate assessments of anti-SARS-CoV-2 immune responses and vaccine efficacy. The second WHO international standard was established after the depletion of the first standard, and the unit has been calibrated against the first standard to 1424 IU/mL.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Covid-19COVID-19, caused by the SARS-CoV-2 virus, has led to a global health crisis with profound impacts on societies and economies. Research into diagnostics, vaccines, treatments, and understanding viral mechanisms continues to evolve. The pandemic has accelerated innovations in healthcare and biopharmaceuticals, including novel vaccine platforms and rapid testing technologies. Browse our peer-reviewed product directory to find top COVID-19 testing kits, research tools, vaccines, and treatments, compare products, read reviews, and receive direct pricing from manufacturers.Vaccines
Calibration of NAB-Sure Neutralizing Antibody Titer using WHO International Standard