Bispecific antibodies and the quantification of their activity using iLite bioassays

In this application note, the use of therapeutic monoclonal antibodies (mAbs) is discussed as treatment for many disorders. The note also outlines how bispecific antibodies (BsAbs) work, how they are useful, and how cell-based reporter-gene assays can be used as valuable tools in the development of new therapeutic BsAbs. Different configurations and functions of BsAbs are also described, including how they work in the lysis of cancer cells.