Automated and efficient isolation of single cells into low volumes for scWGA

5 Aug 2024

Tumors and tumor-derived cancer cell lines comprise a mix of diverse and heterogeneous cells. To interrogate the complex genetic makeup underlying tumorigenesis, cancer progression and metastasis, it is essential that researchers can analyze the genomes of individual cells. A prerequisite for these analyses is whole-genome amplification (WGA). Successful WGA from individual cells requires efficient isolation of single cells and their transfer into low-volume WGA reactions. iotaSciences demonstrates how GRIDs and the scPicking Platform supports the isolation of individual tumor cells for subsequent single-cell WGA (scWGA).

isoPick – Single Cell Isolation

iotaSciences

The isoPick enables gentle single-cell isolation for a range of downstream applications such as single-cell cloning or analysis. Compatible with a variety of cell types, shapes, and sizes, the isoPick allows you to seamlessly acquire your single cells of interest. With a compact footprint, optional sample cooling, and automated handling of small liquid volumes, this instrument delivers the cells that matter to you with ease. 

(0)

scPicking Platform – Single Cell Visualisation and Isolation

iotaSciences

The scPicking Platform facilitates easy visualisation and gentle isolation of your single cells of interest. Compatible with a range of cell types, it allows you to seamlessly acquire your single cells of interest for an array of downstream applications. Offering automated handling of small liquid volumes, optional cooling, imaging, and fluorescence capabilities, it delivers the individual cells that matter to you with ease. 

(0)

Links

Tags

Cell Lines Stem Cells and Primary CellsPrimary cell cultures, established cell lines and stem cells are vital for <i>in vitro</i> and <i>ex vivo</i> experimentation. High-quality cells, optimized for your applications, alongside optimized cell substrates, growth medium and supplements, are critical for experimental success. Explore a range of cells suitable for your applications, including isogenic cell lines, competent cells, induced pluripotent stem cell (iPSC)-derived cell lines, fungal/bacterial/mammalian cell lines, stem cells and cancer cell lines. Find the best cells for your research in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.Single Cell Genomics