ResourceLife Sciences
Assessing Epigenetic Enzyme Activity using HTRF Epigenetic Assays from Cisbio with the PHERAstar <i>FS</i> from BMG LABTECH
19 Aug 2014This application note describes the verification of the performance of a Cisbio HTRF based assay using the PHERAstar FS from BMG LABTECH. This assay allows users to detect the activity of G9a, a histone methyltransferase that methylates histone H3 on lysine 9 (H3K9).
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PHERAstar® FSX HTS Microplate Reader
BMG LABTECHThe most sensitive microplate reader for high-throughput screening
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.HTRF