ResourceLife Sciences
Assessing E. coli-Induced Pharyngeal Pumping in C. elegans using the ScreenChip System
17 May 2017Pharyngeal pumping behavior in C. elegans is employed to ingest bacteria, the worms’ normal food. This application note compares a common method of eliciting pharyngeal pumping – exposing worms to serotonin (5HT) – to an alternative method, seeding plates with the E. coli strain OP50. Pharyngeal pumping frequency was measured from electropharyngeogram (EPG) recordings using the NemaMetrix ScreenChip system. The results demonstrate that using OP50 is a viable alternative to 5HT for stimulating pharyngeal pumping in the ScreenChip.
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In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. Escherichia coliPhenomePhenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.Nematode Worms