ResourceLife Sciences
Assembly and Pharmacological Validation of a Fully Kinetic 96-well In Vitro Vascular Tube Formation Assay
13 Feb 2015In vitro models of vascular tube formation are valuable tools for probing the complex signalling pathways of angiogenesis. This study shows the development of the fibroblast and human umbilical vein endothelial cell (HUVEC) co-culture model into a facile, robust, flexible and fully kinetic 96-well paradigm. This approach is amenable to screening of small molecules, biologics and gene-interference reagents (e.g. siRNA, miRNA).
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Angiogenesis