ResourceDrug discovery > Lead Discovery
Analyzing Aggregation Inhibition by Arginine with the Zetasizer Nano ZSP
27 Oct 2016This application note describes the characterization of a model protein (lysozyme) in the presence and absence of arginine using the array of techniques provided by the Zetasizer Nano ZSP. It details a method for measuring protein aggregation using Static Light Scattering and Dynamic Light Scattering using the Zetasizer Nano ZSP. A distinct advantage of using the Zetasizer Nano ZSP is the ability to analyze protein aggregation quickly and simply, with the high sensitivity of the instrument allowing the earliest stages of aggregation to be characterized.
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Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.AggregationProtein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.Dynamic Light ScatteringDynamic light scattering is used to measure the size distribution of particles in suspension by analyzing the way light scatters off them. It is commonly used in materials science, nanotechnology, and protein characterization. Browse our peer-reviewed product directory to find the best dynamic light scattering systems, compare products, check reviews, and get pricing directly from manufacturers.Protein StructureProtein structure refers to the three-dimensional arrangement of amino acids in proteins, determining their function. Understanding protein structure is key in drug discovery, enzymology, and molecular biology. Explore protein structure analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Protein Stability