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Analysis of Per-and Polyfluoroalkyl Substances (PFAS) Specified in EPA M537.1 Using the Triple Quadrupole LCMS-8045
6 Jun 2019The EPA recently updated Method 537 to 537.1 to incorporate the replacement PFAS introduced into the market after PFOA and PFOS were phased out in the US market. This application note demonstrates that analysis for all analytes listed in EPA 537.1 can be performed on the LCMS-8045, meeting the Quality Assurance and Quality Control criteria specified in the method. Recoveries were greater than 80% for all compounds, with surrogate recoveries within 10% of the true value. Method Detection Limits (MDL) were below 2 ppt for all the target analytes.
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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Environmental ContaminationContaminants in the environment are harmful chemicals that are present in the air, land and water. These include pesticides, pharmaceuticals, persistent organic pollutants (POPs) and many more.Environmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.