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Analysis of oligonucleotide impurities on the BioAccord System with ACQUITY Premier

30 May 2022

This application note demonstrates an automated, compliance-ready LC-MS workflow for purity analysis and intact mass confirmation of extensively modified oligonucleotides and their impurities.

waters_connect

Waters

waters_connect is an informatics platform that helps analytical labs, their scientists, and extended ecosystem explore, discover, and push the boundaries of how laboratories use information.

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BioAccord LC-MS System

Waters

The First SmartMS-Enabled Biopharma Solution  The Waters BioAccord System is an integrated system that simplifies high performance LC-MS biopharmaceutical analysis for every user. An easy-to-use system solution that puts the power to make decisions directly in your hands; a self-calibrating, self-optimizing, self-sufficient tool that equips you with high quality data you can use to tackle the challenges you face every day during biopharmaceutical development.

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Analysis of oligonucleotide impurities on the BioAccord System with ACQUITY Premier