ResourceLife Sciences
Analysis of Integral Membrane Protein–Antibody and Lipid-Protein Interactions Using the ProteOn™ XPR36 Protein Interaction Array System
20 Feb 2015Membrane proteins and membrane-associated proteins and peptides have been shown to be important in many biological processes and are involved in key pathways in diseases such as cancer. Membrane proteins are fast becoming the next big class of drug targets. This poster describes the use of a ProteOn XPR36 protein interaction array system, which uses surface plasmon resonance to measure 36 biomolecular interactions simultaneously, to study the interaction of artificial membranes and two significant peptides.
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Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Membrane Proteins