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Analysis of Drugs: Single Fast Approach for the Determination of Most Common Drugs and Their Metabolites Using GC-TOFMS
31 May 2015The aim of the work in this application note was to develop a complete analytical method using a fast Gas Chromatograph coupled with a Mass Spectrometer with Time Of Flight technology (TOF MS). This system allowed a unique fast analysis (less than 8 minutes) of the most common and used drugs (Cannabis, opioids, opiates and Cocaine), their metabolites and their adulterants from biological and autopsy samples with excellent linearity, sensibility and repeatability.
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GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drugs of AbuseA drug of abuse is a drug that has been taken for non-medical purposes. Such drugs can have mind-altering effects, with some causing dependence and addiction.