ResourceSeparations
Analysis of Drug Substances in Headache Medicines with the PerkinElmer Flexar FX-15 System Equipped with a PDA Detector
30 May 2012This application note presents a modified USP method for the analysis of aspirin, acetaminophen and caffeine using a superficially porous particle column and a PerkinElmer® UHPLC platform. The changes to the USP method are intended to increase the throughput and reduce the solvent consumption.
Links
Tags
UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.USP MethodCaffeineAspirinAcetaminophenHeadache Medicines