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An Introduction to Dynamic Light Scattering Microrheology

19 Apr 2016

This white paper introduces microrheology techniques for the rheological characterization of soft complex fluids, with subsequent emphasis on Dynamic Light Scattering (DLS) Microrheology and the underlying theory. Microrheology techniques involve tracking the motion of dispersed probe (or tracer) particles in a complex fluid, to extract local and bulk rheological properties of the matrix. DLS Microrheology is classified as a passive technique, whereby the colloidal probe particles undergo thermal fluctuations in a system at thermodynamic equilibrium, and offers significant measurement advantages for low viscosity, weakly-structured complex fluids.

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Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.NanotechnologyNanotechnology, or nanotech, is an engineering technique using molecular scale functional systems. Applications of nanotechnology include medicine and medical devices, electronics, air and water purification, food science and energy production.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.RheometryRheometers are used to measure the rheology of fluids, which is the flow of fluids in response to an applied force. The most common types of rheometer include shear rheometers (capillary, cone and plate and rotational cylinder) and extensional rheometers. Viscometers are similar to rheometers however viscometers only measure the viscosity of a fluid.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Dynamic Light ScatteringDynamic light scattering is used to measure the size distribution of particles in suspension by analyzing the way light scatters off them. It is commonly used in materials science, nanotechnology, and protein characterization. Browse our peer-reviewed product directory to find the best dynamic light scattering systems, compare products, check reviews, and get pricing directly from manufacturers.Rheology