ResourceLife Sciences
An Integrated Workflow for Automated Calculation of Antibody‑Drug Conjugate (ADC) Drug‑to-Antibody Ratio (DAR)
25 Jan 2018An easy-to-use and fully integrated method for the determination of drug‑to‑antibody ratios (DARs) of antibody-drug conjugates (ADCs) has been developed using the Agilent AssayMAP Bravo, Agilent MassHunter Walkup software, and the Agilent BioConfirm DAR calculator.
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MassHunter Walkup Software
Agilent TechnologiesAgilent's Walkup Software enables simplified access to the power and precision of high quality LC and LC/MS processes for multiple users.
MassHunter BioConfirm Software
Agilent TechnologiesConfirm the sequence of proteins and post-translational modifications (PTMs), and characterize variants, before you start expensive testing.
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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Development SoftwareComputational techniques used in both the chemistry and biology aspects of drug development, for data acquisition, data analysis, processing and storage. Software is used for analysis of ADME results, toxicology, clinical trials and regulatory processes. Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.Antibody Drug ConjugatesBiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.