ResourceLife Sciences
Amino Acid Fermentation: Evaluation of Scale-Down Capabilities Using DASbox® Mini Bioreactors
28 Nov 2013Optimization of bioprocesses needs accurate monitoring and control while small working volumes are saving
media and other resources. Evonik® has established a 2 L process for production of a nutritionally relevant amino acid in E. coli. The following application note describes how this process was adapted to the smaller working volume of a DASbox Mini Bioreactor System.
Links
Tags
MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.Amino Acids