Agilent automated NGS solutions advance rare disease research at Debré Hospital

21 Mar 2025

Agilent’s automated NGS solutions are accelerating rare disease research at Robert Debré Hospital, Paris. By adopting a single-workflow approach with Agilent advanced automation systems, the hospital is able to process complex samples quickly and accurately, enhancing efficiency and streamlining genomic analysis.

Agilent Solutions for Automated NGS Sample Prep

Agilent Technologies

Agilent Solutions for Automated NGS Sample Prep provide: Flexibility to automate virtually any NGS reagent Performance to dramatically increase throughput and walk-away time Optimized SureSelectXT protocols to rapidly automate your NGS Sample Prep Agilent NGS Option A and Option B Both Deliver Higher Throughput with Less Hands-On Time Automating your NGS sample preparation with either Agilent NGS Option A or Option B increases laboratory throughput up five-fold compared to manual sample preparation. For whole genome sequencing applications that require only library preparation, 96 samples can be prepared in less than 4 hours to increase laboratory output to 960 sequencer ready libraries in a single week. For more complex protocols, such as targeted resequencing using Agilent SureSelectXT, both systems can complete library preparation and target enrichment for 192 samples in a 5-day work week. Agilent NGS Option A: High throughput and improved reproducibility with a small footprint Agilent Bravo Automated Liquid Handling Platform Agilent PlateLoc Thermal Microplate Sealer Agilent Bravo accessories for heating, cooling, shaking, and magnetic separation Agilent NGS Workstation Option B: High throughput and improved reproducibility with more walkaway time Agilent NGS Option A Agilent BenchCel 4R Microplate Handler Agilent Labware MiniHub

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Magnis NGS Prep System

Agilent Technologies

The Magnis system provides a complete workflow for NGS library preparation that is fully automated and delivers reproducible results. Built on proven Agilent SureSelect XT HS2 chemistry, start from total RNA with integrated cDNA conversion or unfragmented DNA with onboard enzymatic fragmentation for increased workflow efficiency.

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Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.NGSNGS AutomationNGS automation streamlines next-generation sequencing workflows, increasing throughput, accuracy, and reproducibility. Automated solutions enhance productivity in genomic research, clinical diagnostics, and personalized medicine. Browse peer-reviewed tools to compare products, read reviews, and get pricing.